Putting patients first – the secret to exceptional results

Today, that vision, combined with the collective expertise and experience of our fertility specialists and support staff, has earned Newlife IVF recognition as one of Victoria’s top-performing IVF clinics.

According to the latest figures reported by the Herald Sun (sourced from the Federal Government’s Your IVF Success website), Newlife IVF holds the highest IVF success rate in Victoria for women under 35, with an impressive 62.5% of embryo transfers resulting in live birth.

For women aged 35 to 42, Newlife IVF also leads with the highest birth rates per embryo transfer in Metropolitan Melbourne (31.7%), placing us third overall in Victoria for this age group.

‘We are delighted to share that we have had another great year for our patients, with our pregnancy and birth success rates consistently above the national average. Our fertility specialist team focuses on providing the best possible milieu for eggs to mature and embryos to implant, and our amazing embryologists focus on every aspect of the egg, sperm and embryo care to provide a nurturing environment to achieve their developmental potential,’ said Dr Nicole Hope, fertility specialist and Medical Director at Newlife IVF.

A vision for exceptional fertility care

As a clinician-owned and led fertility clinic, we’re proud to be one of the few independent specialist fertility centres in Victoria. This independence allows us to offer a more personalised, supportive experience than corporate-owned clinics.

‘We feel so privileged to play a part in our patients’ journeys. Being able to provide a level of care that helps them achieve their dream of starting a family is truly an honour for us,’ said Dr Tiki Osianlis, Newlife IVF’s Managing Director and Scientific Director.

Every aspect of our practice is designed with our patients’ needs in mind. From our state-of-the-art laboratory to our use of advanced scientific tools and techniques, we combine expert-led care with cutting-edge science to give our patients the best possible chance of building the family they dream of.

‘Our IVF success rates highlight how effective our approach is. It’s not just about the science – it’s about the people. The entire team, from our fertility specialists and nurses to our embryologists, counsellors and admin staff, take the time to truly understand each patient’s unique journey. We adapt our care to fit their needs, and every single one of us is genuinely invested in helping our patients achieve their dream of becoming parents,’ said Dr Tiki.

Giving you Newlife in a different way

At Newlife IVF, we believe that everyone deserves the opportunity to build their family, which is why we’re committed to making high-quality fertility treatment as accessible as possible. We remain committed to delivering outstanding results and compassionate care, empowering our patients with the best possible chance of success.

If you’re ready to explore your options for having a baby, you can make an appointment with one of our specialists by calling (03) 8080 8933 or by booking online.

Understanding the IVF process and treatment

Embryologist examining cells under the microscopeWhat is IVF and how does it work?

IVF is an assisted reproductive technique that helps people overcome fertility challenges to start or grow their families. This process involves fertilising an egg with sperm in a specialised laboratory, with the resulting embryo carefully transferred into the uterus with the aim that it will lead to a pregnancy.

Whether you’re just beginning your fertility journey or considering your options, understanding the IVF process is an empowering first step. In this article, we’ll guide you through the process that we use at our fertility clinic in Melbourne, to help you make informed decisions about your next steps.

A step-by-step guide to the IVF process at Newlife IVF in Melbourne

From the initial consultation through to the embryo transfer procedure, IVF involves a series of carefully coordinated stages – tailored to your unique needs – that are designed to give you the best chance of pregnancy success.

Initial consultation with our Melbourne-based fertility specialist

If you’re concerned about your fertility and would like to seek advice from a fertility specialist, you will need a referral from your GP to attend our IVF clinic.

During your initial consultation, your fertility specialist will assess your health and the factors contributing to your fertility issues, as well as provide tailored advice, including recommendations about diet and lifestyle. This process involves taking a thorough medical history from you, performing relevant examinations and ordering appropriate tests. Your fertility specialist will also discuss all available treatment options with you so you can make an informed decision about whether the IVF process is right for you.

If it is decided that IVF treatment is appropriate, we will register you as a patient at our fertility clinic. At this stage, mandatory tests, such as screening for infectious diseases, will be conducted if they have not been done previously.

Personalised fertility treatment planning

As no two fertility journeys are the same, fertility care at our IVF clinic in Melbourne is never one-size-fits-all. Our approach begins with uncovering the root causes of your fertility challenges and guiding you through the treatment options that best suit your unique circumstances. These options can range from straightforward solutions like fertility optimisation and ovulation induction to advanced treatments, such as intrauterine insemination (IUI), IVF, or IVF with intracytoplasmic sperm injection (ICSI).

Ovulation induction and hormone stimulation

Ovulation induction is a commonly used fertility treatment for individuals with ovulatory dysfunction. Often serving as an early intervention, it can be effective as a standalone treatment or combined with others, such as IUI or IVF, to improve the chances of conception. Ovulation induction involves using fertility medication to stimulate your ovaries to produce one or more mature eggs and assist with ovulation. For those undergoing IVF, hormone stimulation with fertility medications is used to stimulate your ovaries to produce a higher number of mature eggs than they normally would. This is a critical step in preparation for egg retrieval.

During this stimulation phase, self-administered hormonal injections are given over 8–14 days to encourage the development of multiple eggs, increasing the number available for retrieval and fertilisation.

Fertility blood tests and monitoring

A fertility specialist performing a pelvic ultrasound on a patient.

Careful monitoring plays a vital role throughout the stimulation phase. Using a combination of blood tests and ultrasounds, your fertility specialist will closely track how your ovaries are responding and how the follicles (sacs in the ovaries that contain eggs) are developing. These tests allow your specialist to assess if everything is progressing as planned and fine-tune your fertility medication to optimise your results.

As you near the end of the stimulation phase, monitoring is used to determine the optimal time for the ‘trigger injection’, which prepares the eggs for ovulation (i.e. their release from the ovaries). Your fertility nurse will liaise with your fertility specialist and guide you on when to administer the injection, as precise timing is essential – the egg retrieval procedure must occur before natural ovulation. Monitoring usually takes place at one of our Newlife IVF locations in Melbourne. However, you don’t have to be in Melbourne to access treatment. We have patients that live in rural or interstate locations and we work with local pathology and ultrasound providers to assist with our patients’ monitoring needs.

Egg retrieval procedure at our IVF clinic in Melbourne

Egg retrieval, also known as egg collection or egg pickup, is a key step in the IVF process. This procedure involves collecting eggs from your ovaries, which can be frozen for future use or fertilised in the next stage of your IVF cycle.

Performed at our IVF clinic under sedation, egg retrieval is a straightforward procedure that typically takes 20–30 minutes. During this time, your fertility specialist carefully collects eggs from your ovaries using a fine needle guided by ultrasound imaging. On average, 8–12 eggs are retrieved, although the exact number depends on factors such as age, ovarian response to the medication and health history.

Collecting multiple eggs at once is important to IVF success. A higher number of eggs increases the chance of developing the healthy embryos needed for a successful embryo transfer and pregnancy.

Our team understands that undergoing egg retrieval can feel both exciting and a little nerve-wracking. But you can rest assured that we’re here to support you every step of the way so that you feel informed and comfortable throughout the entire IVF process.

Sperm collection and ICSI treatment

On the day of egg retrieval, fresh semen samples are collected from the male partner. If you’re using frozen or donor sperm, our embryologists will ensure the sample is thawed and ready for use.

For standard IVF, the semen sample is carefully prepared by removing the seminal fluid (the fluid that contains sperm), isolating the motile sperm and removing immotile sperm before the insemination procedure

For ICSI, the process is more precise. Only a single sperm is used for fertilisation, requiring experienced embryologists to select the healthiest and most viable sperm and inject it directly into the egg.

Selecting the ideal sperm is a delicate process requiring years of expertise. Our embryologists are trained to identify sperm with the best shape and structure to maximise the chances of successful fertilisation.

Fertilisation and embryo development

The next step in the IVF process is fertilisation, where egg and sperm are brought together.

In some cases, depending on the sperm quality and the patient’s previous history, we use standard insemination, where each egg is placed in a laboratory dish and exposed to thousands of prepared sperm. The fittest sperm may then fertilise the egg naturally, mirroring what would occur in the body.

However, if there are challenges such as low sperm count or abnormalities in sperm quality, an advanced technique called ICSI may be used. With ICSI treatment, a single, healthy-looking sperm is carefully injected into an egg to increase the chances of fertilisation. While this method offers additional precision, it’s important to note that not all eggs will successfully fertilise.

If fertilisation occurs, the resulting embryos are carefully placed in an incubator that mimics the conditions of the female body. Over the next five days, these embryos grow and divide, preparing for the next stage of the IVF process – embryo transfer.

The embryo transfer procedure

The embryo transfer is one of the quickest yet most important stages of the IVF process. During this procedure, a carefully selected embryo is placed into your uterus with the hope that it will successfully implant and lead to pregnancy.

Performed under ultrasound guidance, the transfer involves using a long, thin instrument to gently release the embryo through the vagina and cervix into the uterus. For most women, the procedure feels similar to a routine pap test. It is quick, requires no anaesthetic and allows you to resume your usual activities afterwards.

At Newlife IVF, our fertility specialists and embryologists are committed to providing the highest standard of care and technology to maximise your chances of IVF success.

Pregnancy testing and ongoing support

The pregnancy test represents the culmination of weeks of preparation. This fertility blood test measures the level of human chorionic gonadotrophin (hCG) in your body – a hormone produced when a fertilised egg (an embryo) implants into the uterus. Elevated hCG levels can indicate a successful IVF cycle and the achievement of pregnancy.

This test is performed approximately eleven days after the embryo transfer, giving your body the necessary time to respond to implantation. While waiting for results can be an emotional experience, our dedicated team is here to support you regardless of the outcome.

This webinar, presented by fertility specialists Dr Chris Russell and Dr Nicole Hope, provides a more detailed explanation of the IVF process.

 

Why choose Newlife IVF?

At Newlife IVF, we understand how significant the IVF process is, and we’re committed to walking beside you on your journey to parenthood. Whether celebrating your success or exploring the next steps, you’ll always have compassionate care and expert guidance from our team.

Clinician-owned and led fertility clinic in Melbourne

As one of few independent specialist fertility centres in Victoria, we take pride in offering a more personalised, compassionate and supportive experience compared to corporate-owned clinics.

State-of-the-art IVF treatment in Melbourne

Every aspect of our practice is thoughtfully designed with your needs in mind, from our expert-led care to our state-of-the-art laboratory and scientific tools and techniques.

Advanced scientific techniques and high IVF success rates

We incorporate cutting-edge scientific advancements into every step of our IVF treatment process, helping to give you the best possible chance of achieving a successful pregnancy.

Our approach includes the use of the EmbryoScope time-lapse system, which provides continuous monitoring of embryo development, sequential media to nurture embryos, and EmbryoGlue to enhance implantation potential when transferring embryos into the uterus.

For ICSI treatment, we take it a step further with egg spindle visualisation technology, allowing us to carefully select eggs with the greatest potential for fertilisation.

Our IVF success rates reflect the effectiveness of these methods, consistently exceeding the national average and giving our patients a better chance of achieving their dream of parenthood.

Accessible and affordable IVF treatment in Melbourne

At Newlife IVF, we believe that everyone deserves the opportunity to build their family, which is why we are committed to providing affordable IVF treatment. Our fee structure is designed to be transparent and accessible, ensuring that fertility treatment, including IVF, is reasonably priced and doesn’t involve the stress of unexpected costs.

Contact Newlife IVF – your trusted fertility clinic in Melbourne

To book an appointment for IVF treatment in Melbourne with one of our caring, experienced fertility doctors, please call (03) 8080 8933 or email [email protected].

Single and ready to have a baby – what are my options?

I’m a single woman – what are my options?

Donor sperm – clinic-recruited versus known donors

Essentially, there are two options for obtaining sperm: accessing donor sperm through a fertility clinic’s sperm bank, or using a sample provided by someone you know.

At Newlife IVF we have an on-site sperm bank containing samples recruited from local and international donors. The benefit of using sperm from our clinic-recruited donors is that it is thoroughly tested for infectious diseases and common genetic problems. After we freeze the sperm, it is then quarantined before donors are retested to make sure it is high quality and safe to use.

When you use a clinic-recruited donor, you also have the advantage of very clear legal boundaries. The donor has no legal connection to your child – they are not entitled to custody and do not have to pay child support. They also remain anonymous to a large extent; that is, you will not know the donor’s identity (but you will know their family medical history and some of their traits). However, your child can request that the donor’s identity be revealed to them when they turn 18.

If you choose not to go the clinic-recruited donor route, you may consider using a sperm sample from a friend or acquaintance. A benefit of using a known donor is you will likely have a good understanding of their appearance, background and traits. However, the social and legal boundaries are not as clear-cut as they are when using a clinic-recruited donor. Discussing expectations and creating firm boundaries with a known donor requires careful negotiation, and you may wish to seek legal advice on how best to proceed.

If you do decide to use a sample from someone you know, it’s best to involve a fertility clinic. That way, you can have the sample rigorously tested for safety and quality in the same way we test donor sperm.

In this video, Dr Chris Russell talks about donor sperm and its use in IVF and IUI procedures.

Insemination – how egg and sperm meet

The next consideration is how best to introduce the sperm sample to your egg. There are a few different options for insemination, and the most suitable will depend on your specific circumstances.

One possibility is home insemination. In this method, sperm is injected into the vagina using a syringe at home. As this mimics the natural fertilisation process, home insemination is effective when the donor has a normal sperm count. It is also one of the most cost-effective options. However, it does not afford the same degree of protection from infectious disease as undergoing a similar process via a fertility clinic.

The clinic-based alternative is intrauterine insemination (IUI). This is where a sperm sample is concentrated to contain a very high number of sperm. It is then injected directly into your uterus soon after your ovaries release an egg. Using a concentrated sperm sample increases the chances of a sperm fertilising your egg. Depending on your circumstances, your specialist may recommend combining IUI with a medication to stimulate the release of an egg from your ovaries, further increasing the chance of success.

The last option is in vitro fertilisation (IVF). In this process, several of your eggs will be introduced to sperm in laboratory dishes. When utilising clinic-recruited donor sperm, the best sperm may be selected and a single sperm injected directly into each egg, a process called intracytoplasmic sperm injection (ICSI). One of the best embryos resulting from IVF insemination will then be transferred back to your uterus. The rest can be frozen and stored for later use, if necessary.

Two embryologists performing the intracytoplasmic sperm injection procedure.In ICSI, a single sperm is injected into the centre of a mature egg.

There are a few reasons you may be advised to undergo IVF. If you have known infertility, you’re in your late 30s or early 40s (when female fertility naturally declines significantly), or you struggle to get pregnant through other forms of insemination, your specialist may recommend this procedure. Likewise, IVF may be advisable if you’re using a known sperm donor with low sperm quality or quantity for other methods of insemination. If you wish to do preimplantation genetic testing, which is the process of genetically testing your embryos before they are transferred to your uterus, IVF will be necessary. For more information about these procedures in relation to your particular circumstances, chat to your fertility specialist.

I’m a single man – what are my options?

To have a baby as a single man, you will need the help of an egg donor and a surrogate. According to Victorian law, these must be two different women.

You may choose to use a clinic-recruited egg donor, or a known donor, i.e. a friend, acquaintance, or a family member (note: the last is only okay if you are not using your own sperm). Egg donation must be altruistic in Australia, meaning no financial compensation is paid for providing eggs. Once the donor eggs are ready, your sperm will be introduced to them using IVF (discussed earlier in this article), and the best resulting embryo will be transferred to your surrogate’s uterus. If you are not using your own sperm, donor embryos may be an appropriate option for you.

It’s common to ask a friend, acquaintance or family member to be a surrogate. Surrogacy is also an altruistic process in Australia, however ‘reasonable’ medical costs can be paid by you. Keep in mind that in Victoria, multiple medical consultations, counselling sessions and legal advice are required for both you and the surrogate prior to proceeding. You will also need to seek permission from the Patient Review Panel (this is a legal requirement in Victoria), and the sperm or embryos must be quarantined. This process can take several months.

Seeking a surrogate overseas may also be an option. However, according to Australian law, this is only legal if it is altruistic. Be aware that this is a very expensive route and you will need to plan to potentially be overseas for a few months after your baby is born to organise their entry into Australia.

For advice related to your particular circumstances, you may wish to seek legal advice and talk to a fertility specialist. Unfortunately, Newlife IVF is not permitted to assist you in finding a surrogate (nor can any other IVF provider). However, our counsellors can certainly orientate you to the Victorian surrogacy community and provide support and information as you look for a potential surrogate.

Ready to have a baby on your own?

Make an appointment with one of our caring and experienced Newlife IVF fertility specialists to discuss the most appropriate way forward based on your medical history, circumstances and preferences. Call (03) 8080 8933 or book online and take the next step towards your dream.

My doctor says we need ICSI – how will this improve our chances of a successful IVF cycle?

The traditional IVF approach is to allow this meeting to take place ‘naturally’, albeit in a laboratory dish: the woman’s egg is placed in a special culture medium with a prepared semen sample containing thousands of sperm. The fittest sperm fertilises the egg, mimicking what would normally happen in the woman’s reproductive tract.

As its name suggests, ICSI is far more precise. Rather than leaving the egg and sperm to meet of their own accord in a laboratory dish, this technique allows us to directly inject a single sperm into a woman’s egg – thereby, overcoming any issues that may be getting in the way of a sperm and an egg meeting and coming together naturally. Here, we consider some of the reasons why ICSI may be considered during IVF and what specific fertility problems it can help overcome.

Who is ICSI suitable for?

When a couple is experiencing difficulties getting pregnant, it can be easy to focus solely on the woman’s fertility. However, a male factor contributes to infertility in approximately 40% of couples who fail to conceive.1 ‘Male factor infertility’ typically involves an alteration in the number, shape and/or movement of the man’s sperm, all of which can affect the sperm’s ability to fertilise an egg the natural way. ICSI is most commonly used to help overcome these types of sperm-related issues.

ICSI may also sometimes be offered if a woman has very few eggs available (e.g. due to age). In this case, ICSI is used to increase the chances of successful fertilisation, thereby lowering the risk that the woman runs out of eggs before she achieves a successful pregnancy through IVF.

ICSI may also be recommended if one or more previous standard IVF cycles were not successful due to failed fertilisation, or if the reason for cycle failure is unclear but a sperm-related issue is suspected despite a normal semen analysis.2

A checklist for fertile sperm

If your doctor suspects male factor infertility could be affecting your chances of pregnancy, they will usually suggest a semen (sperm) analysis. This is the main method used to test male fertility. During the analysis, a number of different factors that could be affecting your ability to conceive naturally are studied, including:

  • The volume of semen, which needs to be sufficient to transport sperm into the female reproductive tract
  • The sperm concentration and total sperm count, which affect the likelihood that enough sperm will reach the egg in order for one to fertilise it
  • The physical shape of the sperm, as abnormally shaped sperm can have difficulty swimming to the egg or penetrating the egg’s outer layer
  • The motility of the sperm (i.e. how well it can swim) – if large numbers of sperm in the sample are ‘weak swimmers’, then a natural pregnancy will be more difficult to achieve.

Your specialist might also recommend additional testing for:

  • Sperm DNA damage or fragmentation: sperm with damaged or fragmented DNA have a reduced chance of fertilising an egg
  • Sperm antibodies, which if present, can attack and impair sperm function.

Depending on your results, your doctor may then order follow-up tests to make sure the results are accurate and/or to see if anything else is preventing the semen from doing its job.

Once the tests are complete, your specialist will discuss your results with you and explain what your options are, including whether ICSI is likely to increase your chances of successful fertilisation and the overall success of your IVF treatment cycle.

Success rates with ICSI

Because of ICSI, many previously infertile men now have a good chance of fertilising eggs with their sperm. With some couples, pregnancy rates as high as 45% have been achieved with ICSI.3 However, rates this high are not always possible because of other factors, including age and egg quality.

The fertilisation of an egg and its subsequent development into a growing embryo is a complicated process, and there are many reasons why IVF may not be successful, even with the assistance of ICSI. To aid our success rates at Newlife IVF, we:

  1. Ensure an egg is suitable for fertilisation prior to ICSI: Using polarised light microscopy, we assess a structure inside the eggs called a ‘spindle’. We call this ‘egg spindle visualisation’. This allows us to identify if an egg is at a certain stage of development (called metaphase II) and therefore, in optimal condition for fertilisation via ICSI.
  2. Select the healthiest-looking sperm for ICSI: If the genetic information in the sperm has been damaged, or if the sperm is unable to use its DNA correctly, then there is a risk that development of the embryo will fail, even if it has been successfully fertilised via ICSI.4 A number of factors can increase this risk, such as smoking and older age.5,6 It’s not currently possible to know if the sperm we choose for ICSI is completely free of genetic defects. However, by using an advanced imaging system with an extremely high-powered microscope, we are able to study the structure of individual sperm, helping us to select the optimum sperm to inject into an egg. Sometimes, we may also use another technique, called intracytoplasmic morphologically selected sperm injection (IMSI), to help us pick out a healthier sperm based on its shape. A DNA test can also provide us with more details about sperm quality.
  3. Assess the best position to inject the sperm into the egg: Our extremely high-powered microscope also allows us to very precisely inject the selected sperm into the egg, such that we avoid an important structure inside the egg called the spindle. Research has shown that injecting eggs away from the spindle results in higher fertilisation rates and better embryo quality.

Still have questions?

If you are concerned about the possibility of male factor infertility or would like more information about the role of ICSI in an IVF treatment cycle, you can make an appointment with one of our fertility specialists by calling Newlife IVF on (03) 8080 8933. You can also book online via our appointments page.

References


  1. Agerwal A et al. Reprod Biol and Endocrinol. 2015;13:37–46. 
  2. Palermo GD et al. Sem Reprod Med. 2015;33:92–102. 
  3. Palermo GD et al. Sem Reprod Med. 2009;27:191–201. 
  4. Colaco S & Sakkas D. J Assisst Reprod Genet. 2018;35:1953–1968. 
  5. García-Ferreyra J et al. Clin Med Insights. Rep Health 2015;9:21–27. 
  6. Zini A & Sigman M. J Androl 2009;30:219–229.